Genetic Disorders

My genetic disorder was SMA

SMA-stands for Spinal Muscular Atrophy

Affects:

nervous system

voluntary muscle movement- like flexing an arm or a leg

Spinal:affects nerves attached to the spine

Muscular: it doesn't allow for nerves to deliver signals to muscles to work

Atrophy:the term for wastage or shrinkage which happens to the muscles when they aren't active

Causes:

deficiency-doesn't make enough or lacks-of a motor neuron protien

Types:

SMN related SMA

non- SMN SMA

Spinal Bulbar Muscular Atrophy-SBMA =genetic problem on the X chromosome also called kennedy's disease

Type 1 SMA(Werdning-Hoffmann disease) children live approximently 2 years after birth

Type 2 SMA(Intermidiate SMA)

Type 3 SMA(kugelberg-welander disease or mild SMA)

Type 4 SMA(Adult Onset SMA)

Problems:

1 respiratory muscle weakness

2 swallowing muscle weakness

3 back muscle weakness with progressive curvature

4 abnormal reactions to muscle-relaxing medications(anesthesia)

Treatments

1: breathing ventilation devices

2: liquid food & swallowing tube

3: Back brace

4: Use of different drugs

Who can get it:

Any one can get SMA the first types are more common in children where as the last 2 types are common in adults

11/7/2011

homework:

1. comment on a muddiest point by midnight TONIGHT!!!!!!!!!

QUIZ today

Test wednesday make sure to come to class tomorrow(tuesday) with any questions you have!!!!!!!

In class we watched a malaria video:

www.pbs.org/wgbh/rxforsurvival/series/video/d_mal1_dis_malaria1_qt_h.html

Notes:

Active Immunity:

when the body or more specifically plasma B cells produce infection

active immunity comes in two forms

Vaccination:

a weakened form of the pathogen is injected into the body to allow the body to become familiar with the infection so it can be stopped quicker if exposed again

Exposure to the disease:

Allows for primary response to occur and the Memory B/T cells become familiar with the antigens so that secondary response is possible(same as with a vaccine-see above)

Passive Immunity:

When antibodies are obtained passively(through an outside source)

Injections of the antibodies- through a shot at birth or later

Given from mothers to children through breast milk

Passive Immunity is only TEMPORARY there are no memory B/T cells used so no recognition occurs and secondary response doesn't happen

MuddiestPoint

The section was easy to follow so far the only real question is what are protists i mean i know they are agents of disease but what makes them different from the others and how do you identify them?

Scribe 10/13-10/14

HOMEWORK 10/13/11:

• muddiest point post(Friday) and comment(monday)
• cancer paper due 10/25
• sign-up at turnitin.com
• review mitosis

LAB:

In the lab we had to find a example of the stages of mitosis and interphase

IF YOU DIDN'T FINISH UP PAGES 44-47 FINISH THEM!!!!!

HOMEWORK 10/14/11:

• Finish time for mitosis lab (up pages 48-51)
• Muddiest point post(friday) and comment(monday)
• Read 10.3 and up 52b-52d "cause and effect of uncontrolled cell division" multi flow map

HOE TO DO A MULTI FLOW MAP

1. place paper landscape side
2. draw box in center of paper
3. write "cause and effect of uncontrolled cell division" (your subject)
4. look in 10.3 and 52b-54d to find causes and effects
5. places causes on left side of center box in other boxes
6. place effects on right side of other boxes Causes and effects DO NOT have to match
7. for example go to moodle and under reading strategy resources for a picture and example

TIME FOR MITOSIS LAB:

In this lab we took three sections of an onion root under a microscope and counted how many interphase, prophase , metaphase, anaphase, and telophase was seen.

then we put the data into a chart

under the first column labeled first area:

interphase: 128

prophase: 31

metaphase: 0

anaphase: 1

telophase: 10

the second column labeled second area:

interphase 306

prophase 8

metaphase 5

anaphase 9

telophase 5

the third column labeled third area:

interphase 95

prophase 13

metaphase 5

anaphase 1

telophase 3

That's all people

HAPPY HOMECOMING!!!!!!!!!!!!!!!!!!!!!!!!!!!

Muddiest Point

My muddiest point seems to be the organelles i can never tell the difference between ER and Golgi Bodies they just look too similar