Scribe 12/13/11

Today in class we turned in the web quest (UP 83-85) and we turned is as much as we did of it in class.

Here are 3 diseases you can see by looking at the karyotype:

1. Terner Syndrome: ONLY in a girl with 1 X chromosome

2. Down Syndrome: Has an extra chromosome (extra #21 chromosome)

3. Klinefelter Syndrome: Males have 2 X chromosomes which means they have (XXY)

More things we discussed in class include:

• The way you get a trisomy or monosomy is by a problem ("oops") during meiosis called a nondisjunction
• Most cases produce Gametes that are not viable (can't be used)

What is Genetic Engineering?

   Manipulating DNA for practical purposes:

• DNA sequencing and the Human Genome
• Transgenic organisms have many applications in agriculture
• DNA finger printing is used in forensics

   Genetic Engineering Tools:
       PCR:

• Polymerase Chain Reaction (PCR) uses DNA polymerase to make many copies of DNA

       Restriction Enzymes:

• Proteins with recognize and cut SPECIFIC base sequences in DNA
• Results in fragments of DNA with "Sticky Ends"

Later in class we watched a short movie called, "A Not So Perfect Match"

• When they find DNA on a crime they use it to see if they can find a person who has matching DNA or even something close to find a family member

HOMEWORK:

1. Muddiest Points!
2. Test FRIDAY
3. Quiz Retakes by THURSDAY
4. **Remember she will give stamps for UP 73/74 tomorrow**

Next Scribe: KELLI